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The new series finds Monroe (James Nesbitt) and the medical staff at St Matthew's hospital 18 months on from series one. Still the wise cracking,
irreverent and brilliant neurosurgeon he always was, Monroe is about to face a number of changes he could really do without, with new challenges
coming from ex-wife Anna (Susan Lynch - Great Expectations) and son Nick (Perry Millward - Just Henry).
Meanwhile Bremner (Sarah Parish) and Shepherd (Tom Riley) are still a couple and dealing with an unplanned development, which threatens the
future of their relationship and their professional lives.
Monroe's medical trainees, Daniel Springer (Luke Allen-Gale - The Promise) and Kitty Wilson (Michelle Asante - Law & Order: UK) vie to see who will
gain a promotion to become registrar.
Bremner's registrar, Sarah Witney (Christina Chong - Whitechapel) has to hope a rash move doesn't jeopardise her future career whilst Andrew
Mullery (Andrew Gower - Being Human) adjusts to working under Gillespie, and Thomas Morrison (Blackpool) continues to pull everyone's strings as
hospital porter-cum-bookie, Lee Bradley.
The six x 60-minute drama delivers stories laced with humour, which are more emotional than ever, capturing the pressures and intrigue of high-end
surgery in a modern urban hospital.
In the opening episode Paul Herd (Jody Latham - The Street, Shameless) and his pregnant wife Julie (Julia Haworth - Coronation Street) ask Monroe
for help. Paul has been refused surgery by other hospitals for a dangerous neurological condition and Monroe has to decide whether to operate, putting
him in conflict with Gillespie.
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