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It?s 2017, and the undead far outnumber the living in this horror film starring Oscar nominee Ethan Hawke (TRAINING DAY). A virus has spread across the earth, turning its inhabitants into vampires?. Ten years after a plague turns most of the world?s population into vampires, a critical blood shortage causes panic and gruesome mutations among the reanimated. Edward (Ethan Hawke), a vampire hematologist, tries to develop a blood substitute when  he meets Lionel (Willem Dafoe) and Audrey (Claudia Karvan), two fugitive humans who claim to have a possible cure. Edward casts his lot with them in the hope of perfecting the cure before it?s too late.